Glanzmann's thrombasthenia: pathogenesis, diagnosis, and current and emerging treatment options
نویسندگان
چکیده
منابع مشابه
Glanzmann’s thrombasthenia: pathogenesis, diagnosis, and current and emerging treatment options
Glanzmann's thrombasthenia (GT) is a genetic platelet surface receptor disorder of GPIIb/IIIa (ITG αIIbβ3), either qualitative or quantitative, which results in faulty platelet aggregation and diminished clot retraction. Spontaneous mucocutaneous bleeding is common and can lead to fatal bleeding episodes. Control and prevention of bleeding among patients with GT is imperative, and remains chall...
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ژورنال
عنوان ژورنال: Journal of Blood Medicine
سال: 2015
ISSN: 1179-2736
DOI: 10.2147/jbm.s71319